Stem cell platform specialist company 'Cell Research' announced on the 27th that it has officially signed a domestic joint clinical partnership agreement for 'Kalresim', a hair loss and skin regeneration solution, with Cheongdam Yuseong Plastic Surgery Center (CDU), famous for its plastic surgery clinic for celebrities.
'CALECIM' is a hair loss and skin regeneration solution based on the stem cell super exosome 'PTT-6' developed by Cell Research. It was recently unveiled for the first time at the '2025 Korean Society of Laser Dermatology and Hair Loss' (Daepimo) international conference, drawing great interest from dermatologists and plastic surgeons. As a result of receiving applications for clinical trial participation from medical staff attending the conference, 1,000 hospitals in Korea submitted letters of intent to participate in the clinical trial in just 3 hours, becoming a hot topic.
Cellsearch plans to fully support the clinical trial of Kalesim by 'Cheongdam Yuseong Plastic Surgery Center', a joint clinical partner in Korea, together with 'Key & Stone', the exclusive domestic supplier of Kalesim. The clinical results are planned to be announced at dermatology and plastic surgery academic societies, and also shared with approximately 4,500 Kalesim clinical affiliate hospitals around the world.
Cell Research is a global stem cell platform company headquartered in Singapore. It is a leading company that has maintained unrivaled technology in the field of umbilical cord stem cells through research and development for over 20 years. It is currently being used for clinical and therapeutic purposes in over 4,500 hospitals and clinics in over 40 countries including the US, UK, Australia, and Hong Kong. It is currently pursuing a NASDAQ listing, and its corporate value is approximately KRW 1 trillion.
'Cheongdam Yu Plastic Surgery Center' (CDU) is a plastic surgery clinic run by Oakwood Spring Clinic. It is highly trusted as it has many top-tier plastic surgeons from professional academic organizations such as the Korean Society of Plastic and Reconstructive Surgery, the Korean Society of Aesthetic Plastic Surgery, the Korean Society of Craniofacial Plastic Surgery, and the American Society of Plastic and Reconstructive Surgeons. It is also famous as a 'celebrity plastic surgery clinic' frequented by popular celebrities.
In addition, CDU operates a post-treatment recovery system called 'CDU COMPLETE', providing patients with a premium recovery platform that helps suppress inflammation and restore tissue through stem cell-based treatment, hyperbaric oxygen therapy, and immune nutrition therapy.
Cellsearch plans to apply Calesim as a core component in the skin and tissue recovery area within the 'CDU COMPLETE' system, and to expand its indications to the field of regenerative medicine, including skin regeneration, wound healing, and inflammation suppression, in addition to existing high-difficulty cosmetic procedures.
'PTT-6', the core component of Kalesim, is a next-generation super exosome platform that highly concentrates approximately 3,000 types of physiologically active substances, including exosomes, growth factors, microRNA, and anti-inflammatory cytokines secreted from umbilical cord-derived stem cells. It is characterized by promoting the natural regeneration process through multiple mechanisms that simultaneously induce various physiological responses, such as tissue regeneration, inflammation control, and collagen remodeling.
Yang Dong-jun, the director (MD) of Cheongdam Yuseong Plastic Surgery Center, said, “We have always approached patients with an open attitude if there is a treatment that can help them,” and “Kalesim is not just a new technology, but is well-suited to our philosophy of recovery-centered treatment that we have pursued. It will be an important clue that can further increase patient satisfaction in the future.”
“To prove the real value of the stem cell platform, we need a partner with excellent surgical skills and deep clinical insight,” said Ivo Lim, MD, Plastic Surgeon and Co-founder of Cell Research. “Korea is one of the countries with the most advanced plastic surgery technology in the world. The CDU medical team is a world-class team with both clinical skills and aesthetic sense. We are honored and excited to explore the new possibilities of PTT-6.”
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